There are crying needs for a new semantics which extends the methodology of denotational semantics and domain theory to the challenges in analyzing computation today. If semantics is to encompass operational concerns adequately it has to be an {\em intensional} theory, capturing the {\em ways} in which computation proceeds and not merely input and output. The evidence for this comes from: sequential programming, where \eg~game semantics informs operational semantics; interactive/distributed computation, where \eg~analysis of security protocols often relies on clever encryption to ensure desired event dependencies; from anomalies, as in nondeterministic dataflow, where intensionality is forced in order to achieve a compositional semantics. This intensionality would immediately set the next generation of semantics apart from traditional domain theory and denotational semantics. Once achieved it would make the current distinctions between operational and denotational semantics disappear; a denotation would carry its operational semantics. But what form should the next generation of semantics take? This talk will outline beginning ideas and an ERC research programme to find out.